Learn about side effects, drug interactions, dosages, warnings, and more. We comply with the HONcode standard for trustworthy health information -, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. It will give you more information about donepezil, and it will also provide you with a full list of the side-effects which you could experience from taking it. Donepezil was approved for … Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Proper use of donepezil. Lam W "Pharmacological treatment of cognitive deficits in Alzheimer's disease." Common side … What should I know about storage and disposal of this medication? Int J Clin Pharmacol Ther Toxicol 31 (1993): 223-9, 13. Possible side effects 5. These side effects may go away during treatment as your body adjusts to the medicine. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. Donepezil may cause other side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Heart Block 17. Cataracts 9. J Am Geriatr Soc 57 (2009): 565. Distribution: Volume of distribution: 12-16 L/kg. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). Along with its needed effects, a medicine may cause some unwanted effects. Some side effects may not be reported. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. For full details of side effects and contraindications, see the Summary of Product The side effects are usually mild and will disappear if the person continues on the medication. J Clin Psychiatry 63 (2002): 250-1, 8. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 3. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Pregúntele a su médico o farmacéutico si no sabe si un medicamento al que es alérgico es un medicamento piperidina. J Neurol Neurosurg Psychiat 66 (1999): 410, 11. Possible side effects 5 How to store Donepezil hydrochloride 6. Below is a summary of known side effects for Donepezil. For more information, ask the doctor or pharmacist. Cerner Multum, Inc. "Australian Product Information." This content does not have an English version. INFREQUENT side effects An Increased Need To Urinate Often Arthritis Decreased Appetite Dizziness Fainting Low Energy Aggressive Behavior 3. [Ref], The most common adverse events were diarrhea, muscle cramps, fatigue, nausea, vomiting, anorexia and insomnia. Adverse reactions reported as more than an isolated case are listed below, by system organ class and by frequency. Medically reviewed by Drugs.com. Donepezil is not mutagenic in bacterial and mammalian cell mutation assays. If you forget to take Donepezil tablets Do … Ann Pharmacother 32 (1998): 610-11, 14. Extreme Loss Of Body Water 14. "Product Information. Kawashima T, Yamada S "Delirium caused by donepezil: a case study." Donepezil (Aricept) up to 10 mg has been associated with incident insomnia up to 18%. Some clastogenic effects were observed in vitro at concentrations overtly toxic to the cells and more than 3000 times the steady-state plasma concentrations. This site complies with the HONcode standard for trustworthy health information: verify here. Usar un AINE con donepezil puede aumentar su riesgo de úlcera gástrica. This medicine may cause some people to become dizzy or drowsy, to have blurred vision, or to have problems with clumsiness or unsteadiness. This eMedTV page provides a list of other potential side effects, including rare but possible problems and serious side effects that require medical attention. All rights reserved. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media These side effects may go away during treatment as your body adjusts to the medicine. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Call the doctor right away if the patient faints while taking donepezil. 2. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Safe use of Aricept during pregnancy has not been established. Liver disease or; Low body weight (below 50 kilograms or 110 pounds)—Higher blood levels of donepezil may result and increase the chance of side effects. Because there have been limited trials of donepezil in MS and the results have been mixed, the current evidence of the efficacy of donepezil on cognitive function in people with MS is unclear.